Title
Fair and Privacy-Preserving Alzheimer's Disease Diagnosis Based on Spontaneous Speech Analysis via Federated Learning.
Abstract
As the most common neurodegenerative disease among older adults, Alzheimer's disease (AD) would lead to loss of memory, impaired language and judgment, gait disorders, and other cognitive deficits severe enough to interfere with daily activities and significantly diminish quality of life. Recent research has shown promising results in automatic AD diagnosis via speech, leveraging the advances of deep learning in the audio domain. However, most existing studies rely on a centralized learning framework which requires subjects' voice data to be gathered to a central server, raising severe privacy concerns. To resolve this, in this paper, we propose the first federated-learning-based approach for achieving automatic AD diagnosis via spontaneous speech analysis while ensuring the subjects' data privacy. Extensive experiments under various federated learning settings on the ADReSS challenge dataset show that the proposed model can achieve high accuracy for AD detection while achieving privacy preservation. To ensure fairness of the model performance across clients in federated settings, we further deploy fair aggregation mechanisms, particularly q-FEDAvg and q-FEDSgd, which greatly reduces the algorithmic biases due to the data heterogeneity among the clients. Clinical Relevance -The experiments were conducted on publicly available clinical datasets. No humans or animals were involved.
Year
DOI
Venue
2022
10.1109/EMBC48229.2022.9871204
Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
DocType
Volume
ISSN
Conference
2022
2694-0604
Citations 
PageRank 
References 
0
0.34
0
Authors
5
Name
Order
Citations
PageRank
Syed Irfan Ali Meerza100.34
Zhuohang Li201.01
Luyang Liu322.05
Jiaxin Zhang403.04
Jian Liu503.38