Title
AI-ML applications in bioprocessing: ML as an enabler of real time quality prediction in continuous manufacturing of mAbs
Abstract
•Machine learning techniques enable real time process control and product quality prediction.•Proposed method assists process development in accordance with QbD approach.•Tree based regression techniques outperformed neural network and gradient boosting techniques.•Gradient boosting regression model performance depends on hyperparameters tuning.•Neural network requires large datasets for training and validation.
Year
DOI
Venue
2022
10.1016/j.compchemeng.2022.107896
Computers & Chemical Engineering
Keywords
DocType
Volume
DNN,SVR,Random forest,Decision tree,Machine learning,Monoclonal antibody (MAB)
Journal
164
ISSN
Citations 
PageRank 
0098-1354
0
0.34
References 
Authors
0
6
Name
Order
Citations
PageRank
Saxena Nikita100.34
Garima Thakur200.34
Naveen G Jesubalan300.34
Amey Kulkarni400.34
Vinesh B. Yezhuvath500.34
Anurag S Rathore600.34