Name
Title | ||
|---|---|---|
DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data. |
Abstract | ||
|---|---|---|
Drug versus Disease (DvD) provides a pipeline, available through R or Cytoscape, for the comparison of drug and disease gene expression profiles from public microarray repositories. Negatively correlated profiles can be used to generate hypotheses of drug-repurposing, whereas positively correlated profiles may be used to infer side effects of drugs. DvD allows users to compare drug and disease signatures with dynamic access to databases Array Express, Gene Expression Omnibus and data from the Connectivity Map. |
Year | DOI | Venue |
|---|---|---|
2013 | 10.1093/bioinformatics/bts656 | BIOINFORMATICS |
Field | DocType | Volume |
Data mining,Drug repositioning,Computer science,Bioconductor,Bioinformatics,Gene expression profiling,R package,Gene expression omnibus | Journal | 29 |
Issue | ISSN | Citations |
1 | 1367-4803 | 10 |
PageRank | References | Authors |
0.73 | 3 | 7 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Clare Pacini | 1 | 10 | 0.73 |
| Francesco Iorio | 2 | 53 | 6.89 |
| Emanuel Goncalves | 3 | 82 | 4.83 |
| Murat Iskar | 4 | 80 | 4.95 |
| Thomas Klabunde | 5 | 18 | 2.98 |
| Peer Bork | 6 | 4451 | 694.12 |
| Julio Saez-Rodriguez | 7 | 911 | 67.01 |