Paper Info
Title
Poster: HORIBALFRE: Higher Order Residue Interactions Based ALgorithm for Fold REcognition
Abstract
In an attempt to enhance the potential based fold - recognition methods of remote homologs, we propose a new approach “Higher Order Residue Interaction Based ALgorithm for Fold REcognition (HORIBALFRE)”, where we incorporated the potential contributions not just from one-body and two-body terms, but from three body (triplet interactions) and four-body (quadruple interaction) interactions, to implement a new fold recognition method. Core of HORIBALFRE includes the potentials generated from a structure library derived from CAMPASS database of structure based sequence alignment. Currently, the algorithm is applied to the Fischer's dataset. Our preliminary result indicates that inclusion of higher order residue interaction (quadruple) potentials increases the prediction performance.
Year
DOI
Venue
2011
10.1109/ICCABS.2011.5729916
Computational Advances in Bio and Medical Sciences
Keywords
Field
DocType
quadruple interaction,potential contribution,recognition method,higher order residue interaction,structure library,fold recognition,campass database,triplet interaction,prediction performance,new approach,materials,higher order,bioinformatics,web server,sequence alignment,molecular biophysics,proteins,computational biology,databases
Sequence alignment,Residue (complex analysis),Threading (protein sequence),Algorithm,Chemistry,Molecular biophysics,Bioinformatics
Conference
ISBN
Citations 
PageRank 
978-1-61284-851-8
0
0.34
References 
Authors
1
5
Name
Order
Citations
PageRank
Pandurangan Sundaramurthy1131.02
Raashi Sreenivasan2131.02
Khader Shameer3805.14
S. Gakkhar4257.10
Ramanathan Sowdhamini521521.20