Title
Articulated planar reformation for change visualization in small animal imaging.
Abstract
The analysis of multi-timepoint whole-body small animal CT data is greatly complicated by the varying posture of the subject at different timepoints. Due to these variations, correctly relating and comparing corresponding regions of interest is challenging.In addition, occlusion may prevent effective visualization of these regions of interest. To address these problems, we have developed a method that fully automatically maps the data to a standardized layout of sub-volumes, based on an articulated atlas registration. We have dubbed this process articulated planar reformation, or APR. A sub-volume can be interactively selected for closer inspection and can be compared with the corresponding sub-volume at the other timepoints, employing a number of different comparative visualization approaches. We provide an additional tool that highlights possibly interesting areas based on the change of bone density between timepoints. Furthermore we allow visualization of the local registration error, to give an indication of the accuracy of the registration. We have evaluated our approach on a case that exhibits cancer-induced bone resorption.
Year
DOI
Venue
2010
10.1109/TVCG.2010.134
IEEE Trans. Vis. Comput. Graph.
Keywords
Field
DocType
articulated atlas registration,different comparative visualization approach,small animal imaging,corresponding sub-volume,local registration error,articulated planar reformation,cancer-induced bone resorption,effective visualization,ct data,subjectat different timepoints,bone densitybetween timepoints,change visualization,corresponding region,data analysis,computed tomography,data visualization,bone resorption,layout,image registration,molecular biophysics,data visualisation,molecular imaging,region of interest
Computer vision,Data visualization,Visualization,Computer science,Planar,Artificial intelligence,Computed tomography,Animal imaging,Image registration
Journal
Volume
Issue
ISSN
16
6
1077-2626
Citations 
PageRank 
References 
13
0.70
18
Authors
8
Name
Order
Citations
PageRank
Peter Kok1130.70
Martin Baiker2413.92
Emile A. Hendriks326130.44
Frits H. Post41389111.99
Jouke Dijkstra512616.92
Clemens W G M Löwik6222.05
B.P.F. Lelieveldt71331115.59
Charl P. Botha818219.15