Title
Epoch: an ontological framework to support clinical trials management
Abstract
The increasing complexity of clinical trials has generated an enormous requirement for knowledge and information specification at all stages of the trials, including planning, documentation, implementation, and analysis. We are building a knowledge-based framework (Epoch) to support the management of clinical trials. We are tailoring this approach to the Immune Tolerance Network (ITN), an international research consortium developing new therapeutics in immune-mediated disorders. In the broad spectrum of trial management activities, we currently target two areas that are vital to the successful implementation of a trial: (1) tracking study participants as they advance through the trials, and (2) tracking biological specimens as they are processed at the trial laboratories. The core of our software architecture is a suite of ontologies that conceptualizes relevant clinical trial domain. Our approach can provide ITN and other research organizations a stable and consistent knowledge source for clinical-trial software applications.
Year
DOI
Venue
2006
10.1145/1183568.1183574
HIKM
Keywords
Field
DocType
trial management activity,international research consortium,consistent knowledge source,research organization,trial laboratory,clinical-trial software application,clinical trials management,clinical trial,relevant clinical trial domain,successful implementation,software architecture,ontological framework,ontology,knowledge base,spectrum,owl
Ontology (information science),Ontology,Suite,Computer science,Clinical trial,Knowledge management,Software,Software architecture,Knowledge base,Documentation
Conference
ISBN
Citations 
PageRank 
1-59593-528-2
14
1.11
References 
Authors
8
5
Name
Order
Citations
PageRank
R. Shankar1110496.32
Susana B. Martins213517.13
Martin J. O'Connor353657.50
David B. Parrish4455.35
Amar K. Das542051.09