Name
Abstract | ||
|---|---|---|
Motivation: The computational identification of transcription factor binding sites is a major challenge in bioinformatics and an important complement to experimental approaches. Results: We describe a novel, exact discriminative seeding DNA motif discovery algorithm designed for fast and reliable prediction of cis-regulatory elements in eukaryotic promoters. The algorithm is tested on biological benchmark data and shown to perform equally or better than other motif discovery tools. The algorithm is applied to the analysis of plant tissue-specific promoter sequences and successfully identifies key regulatory elements. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1093/bioinformatics/btn444 | BIOINFORMATICS |
Keywords | Field | DocType |
binding sites,algorithms,computational biology,transcription factors | Promoter,DNA binding site,Computer science,Sequence motif,Bioinformatics,Seeder,Discriminative model,Perl | Journal |
Volume | Issue | ISSN |
24 | 20 | 1367-4803 |
Citations | PageRank | References |
12 | 0.61 | 14 |
Authors | ||
3 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| François Fauteux | 1 | 12 | 0.61 |
| Mathieu Blanchette | 2 | 631 | 62.65 |
| Martina V Strömvik | 3 | 17 | 2.91 |