Title
PROTEAN: Deriving Protein Structure from Constraints
Abstract
PROTEAN is an evolving knowledge-based system that is intended to identify the three-dimensional conformations of proteins in solution. Using a variety of empirically derived constraints, PROTEAN must identify legal positions for each of a protein's constituent structures (e.g., atoms, amino acids, helices) in three- dimensional space. In fact, because protein-structure analysis is an underconstrained problem, PROTEAN must identify the entire family of conformations allowed by available constraints. In this paper, we discuss PROTEAN's approach to the protein-structure analysis problem and its current implementation within the BBl blackboard architecture.
Year
Venue
Keywords
1986
AAAI
amino acid,knowledge based system,blackboard architecture,protein structure,three dimensional
Field
DocType
Citations 
Computer science,Blackboard system,Helix,Artificial intelligence,Protein structure
Conference
28
PageRank 
References 
Authors
8.16
1
9
Name
Order
Citations
PageRank
Barbara Hayes-Roth11465510.58
Bruce G Buchanan21473777.28
Olivier Lichtarge318218.68
Mike Hewitt415319.66
Russ B. Altman52500456.07
James F. Brinkley6429104.67
Craig Cornelius73710.87
Bruce S. Duncan84111.76
Oleg Jardetzky9349.32