Title | ||
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TTA Lynx: a web-based service for analysis of actinomycete genes containing rare TTA codon. |
Abstract | ||
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Motivation: TTA Lynx is a web-based service for finding, assessing and comparing coding sequences that contain TTA codons. This codon is most notable for being a regulatory switch that governs different aspects of the physiology of several GC-rich, Gram-positive bacteria belonging to genus Streptomyces, prolific producers of clinically important natural products. The ever-increasing pace of genome sequencing is creating a huge volume of data that could be utilized to improve our understanding of rare codons in actinomycete biology ( and other biological systems.) The service described here is designed to facilitate analysis of TTA-containing genes and to assess the importance of TTA-mediated regulation in an organism of interest. This service and its database of organisms with well-known or hypothetical TTA-based regulation provides an opportunity for the identification of such regulation on a genome-wide scale. |
Year | DOI | Venue |
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2009 | 10.1093/bioinformatics/btp402 | BIOINFORMATICS |
Field | DocType | Volume |
Data mining,Gene,Biology,Genus Streptomyces,DNA sequencing,Bioinformatics,Web service,Organism | Journal | 25 |
Issue | ISSN | Citations |
18 | 1367-4803 | 0 |
PageRank | References | Authors |
0.34 | 2 | 3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Nestor Zaburannyy | 1 | 0 | 0.34 |
Bohdan Ostash | 2 | 0 | 0.34 |
Victor Fedorenko | 3 | 0 | 0.34 |