Title
Automatic Registration Of Whole Body Serial Micro Ct Images With A Combination Of Point-Based And Intensity-Based Registration Techniques
Abstract
Registration of image volumes acquired over time is important for tasks that include measurements and quantification of temporal changes such as variations in tumor size, shape, or characteristics in response to therapy. A number of methods have been proposed over the years to address this problem but whole body registration of small animals presents special challenges because these images contain many articulated joints and because the animals cannot be easily placed in the same position from acquisition to acquisition. This paper presents a new method for the automatic registration of whole body CT volumes, which consists of two steps. Skeletons are first brought in approximate correspondence with a point-based method. Transformations so obtained are refined with an intensity-based algorithm. The approach has been tested on serial image volumes of a mouse acquired with a micro CT. We demonstrate that the approach we propose can successfully register image volumes even when the limbs are in very different positions as is often the case for small animals.
Year
DOI
Venue
2006
10.1109/ISBI.2006.1624951
2006 3RD IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: MACRO TO NANO, VOLS 1-3
Keywords
Field
DocType
time measurement,computed tomography,image registration,skeleton
Computer vision,Pattern recognition,Computer science,Volume measurement,Medical treatment,Artificial intelligence,Computed tomography,Automatic image registration,Image registration
Conference
ISSN
Citations 
PageRank 
1945-7928
9
0.57
References 
Authors
11
4
Name
Order
Citations
PageRank
Xia Li1163.19
Todd E. Peterson23610.02
John C Gore361641.36
Benoit M. Dawant41388223.11