Title
Whole genome assembly from 454 sequencing output via modified DNA graph concept.
Abstract
Recently, 454 Life Sciences Corporation proposed a new biochemical approach to DNA sequencing (the 454 sequencing). It is based on the pyrosequencing protocol. The 454 sequencing aims to give reliable output at a low cost and in a short time. The produced sequences are shorter than reads produced by classical methods. Our paper proposes a new DNA assembly algorithm which deals well with such data and outperforms other assembly algorithms used in practice.
Year
DOI
Venue
2009
10.1016/j.compbiolchem.2009.04.005
Computational Biology and Chemistry
Keywords
Field
DocType
DNA assembly,454 sequencing,DNA graph
Shotgun sequencing,Hybrid genome assembly,DNA sequencing theory,Paired-end tag,Biology,Whole genome sequencing,Bioinformatics,Genetics,k-mer,Sequence assembly,Sequencing by hybridization
Journal
Volume
Issue
ISSN
33
3
1476-9271
Citations 
PageRank 
References 
6
0.52
13
Authors
10
Name
Order
Citations
PageRank
Jacek Blazewicz11064154.23
Marcin Bryja260.52
Marek Figlerowicz3192.52
Piotr Gawron44711.23
Marta Kasprzak530629.54
Edward Kirton660.52
Darren Platt781.31
Jakub Przybytek860.52
Aleksandra Swiercz9394.54
Lukasz Szajkowski1091.32