Name
Abstract | ||
|---|---|---|
Teleost fishes share a duplication of their entire genomes. We report here on a computational survey of structured non-coding RNAs (ncRNAs) in teleost genomes, focusing on the fate of fish-specific duplicates. As in other metazoan groups, we find evidence of a large number (11,543) of structured RNAs, most of which (~86%) are clade-specific or evolve so fast that their tetrapod homologs cannot be detected. In surprising contrast to protein-coding genes, the fish-specific genome duplication did not lead to a large number of paralogous ncRNAs: only 188 candidates, mostly microRNAs, appear in a larger copy number in teleosts than in tetrapods, suggesting that large-scale gene duplications do not play a major role in the expansion of the vertebrate ncRNA inventory. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1142/S0219720008003886 | J. Bioinformatics and Computational Biology |
Keywords | Field | DocType |
non-coding rna,annotation,ncrna,ncrna evolution,teleosts,ncrna gene finding,teleost fish,comparative genomics,takifugu rubripes,whole-genome duplication | Genome,RNA,Gene,Biology,Gene dosage,Comparative genomics,Vertebrate,Bioinformatics,Gene duplication,Genetics,Non-coding RNA | Journal |
Volume | Issue | ISSN |
6 | 6 | 0219-7200 |
Citations | PageRank | References |
1 | 0.36 | 13 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Dominic Rose | 1 | 33 | 3.53 |
| Julian Jöris | 2 | 1 | 0.36 |
| Jörg Hackermüller | 3 | 149 | 9.93 |
| Kristin Reiche | 4 | 165 | 8.22 |
| Qiang Li | 5 | 84 | 19.63 |
| Peter F. Stadler | 6 | 1839 | 152.96 |