Paper Info
Title
String 8-A Global View On Proteins And Their Functional Interactions In 630 Organisms
Abstract
Functional partnerships between proteins are at the core of complex cellular phenotypes, and the networks formed by interacting proteins provide researchers with crucial scaffolds for modeling, data reduction and annotation. STRING is a database and web resource dedicated to protein-protein interactions, including both physical and functional interactions. It weights and integrates information from numerous sources, including experimental repositories, computational prediction methods and public text collections, thus acting as a meta-database that maps all interaction evidence onto a common set of genomes and proteins. The most important new developments in STRING 8 over previous releases include a URL-based programming interface, which can be used to query STRING from other resources, improved interaction prediction via genomic neighborhood in prokaryotes, and the inclusion of protein structures. Version 8.0 of STRING covers about 2.5 million proteins from 630 organisms, providing the most comprehensive view on protein-protein interactions currently available. STRING can be reached at http://string-db.org/.
Year
DOI
Venue
2009
10.1093/nar/gkn760
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
data reduction,protein protein interaction,protein structure,proteins,genomics
Genome,Web resource,Query string,Annotation,Biology,Metadatabase,Prokaryotic cells,Genomics,Genetics,Protein structure
Journal
Volume
Issue
ISSN
37
Database-Issue
0305-1048
Citations 
PageRank 
References 
234
14.45
20
Authors
12
Search Limit
100234
Name
Order
Citations
PageRank
Lars Juhl Jensen12202137.56
Michael Kuhn2174189.75
Manuel Stark350025.71
Samuel Chaffron435523.76
C. J. Creevey530921.31
Jean Muller667138.15
Tobias Doerks71093163.46
P Julien831720.15
Alexander Roth987448.92
Milan Simonovic10101344.33
Peer Bork114451694.12
Christian von Mering121905119.64