Name
Abstract | ||
|---|---|---|
We developed a package TripletSearch to compute relationships within triplets of genes based on Roundup, an orthologous gene database containing >1500 genomes. These relationships, derived from the coevolution of genes, provide valuable information in the detection of biological network organization from the local to the system level, in the inference of protein functions and in the identification of functional orthologs. To run the computation, users need to provide the GI IDs of the genes of interest.http://wall.hms.harvard.edu/sites/default/files/tripletSearch.tar.gzdpwall@hms.harvard.eduSupplementary data are available at Bioinformatics online. |
Year | DOI | Venue |
|---|---|---|
2011 | 10.1093/bioinformatics/btr485 | Bioinformatics |
Keywords | Field | DocType |
supplementary data,gz contact,package tripletsearch,bioinformatics online,functional orthologs,biological network organization,orthologous gene database,functional gene orthologs,protein function,gi ids,supplementary information | Genome,Gene,Inference,Biological network,Computer science,Genomics,Homology (biology),Orthologous Gene,Bioinformatics,Phylogenetics | Journal |
Volume | Issue | ISSN |
27 | 20 | 1367-4811 |
Citations | PageRank | References |
1 | 0.47 | 5 |
Authors | ||
4 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Jike Cui | 1 | 9 | 1.73 |
| Todd F. DeLuca | 2 | 41 | 4.08 |
| Jae-Yoon Jung | 3 | 297 | 31.94 |
| Dennis P. Wall | 4 | 169 | 22.14 |