Title
Prediction Of An Ribosomal-Rna Methyltransferase Domain In Human Tumor-Specific Nucleolar Protein P120
Abstract
Using computer methods for identification of amino acid motifs in sequence databases and multiple alignment, it is shown that human proliferation-associated nucleolar protein P120 contains a putative methyltransferase domain that is conserved in a group of bacterial proteins. It is hypothesized that P120 and the related prokaryotic proteins are rRNA methylases required for division of all types of cells.
Year
DOI
Venue
1994
10.1093/nar/22.13.2476
NUCLEIC ACIDS RESEARCH
Keywords
Field
DocType
amino acid sequence,methyltransferases,nuclear proteins
Sequence alignment,TRNA Methyltransferases,Biology,Ribosomal RNA,Biochemistry,Nuclear protein,Homology (biology),Multiple sequence alignment,Genetics,Molecular biology,Peptide sequence,Nucleolus
Journal
Volume
Issue
ISSN
22
13
0305-1048
Citations 
PageRank 
References 
0
0.34
0
Authors
1
Name
Order
Citations
PageRank
Eugene V. Koonin1986239.69