Title | ||
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Prediction Of An Ribosomal-Rna Methyltransferase Domain In Human Tumor-Specific Nucleolar Protein P120 |
Abstract | ||
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Using computer methods for identification of amino acid motifs in sequence databases and multiple alignment, it is shown that human proliferation-associated nucleolar protein P120 contains a putative methyltransferase domain that is conserved in a group of bacterial proteins. It is hypothesized that P120 and the related prokaryotic proteins are rRNA methylases required for division of all types of cells. |
Year | DOI | Venue |
---|---|---|
1994 | 10.1093/nar/22.13.2476 | NUCLEIC ACIDS RESEARCH |
Keywords | Field | DocType |
amino acid sequence,methyltransferases,nuclear proteins | Sequence alignment,TRNA Methyltransferases,Biology,Ribosomal RNA,Biochemistry,Nuclear protein,Homology (biology),Multiple sequence alignment,Genetics,Molecular biology,Peptide sequence,Nucleolus | Journal |
Volume | Issue | ISSN |
22 | 13 | 0305-1048 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
1 |
Name | Order | Citations | PageRank |
---|---|---|---|
Eugene V. Koonin | 1 | 986 | 239.69 |