Name
Title | ||
|---|---|---|
A MATLAB-based tool for accurate detection of perfect overlapping and nested inverted repeats in DNA sequences. |
Abstract | ||
|---|---|---|
Palindromic sequences, or inverted repeats (IRs), in DNA sequences involve important biological processes such as DNA-protein binding, DNA replication and DNA transposition. Development of bioinformatics tools that are capable of accurately detecting perfect IRs can enable genome-wide studies of IR patterns in both prokaryotes and eukaryotes. Different from conventional string-comparison approaches, we propose a novel algorithm that uses a cumulative score system based on a prime number representation of nucleotide bases. We then implemented this algorithm as a MATLAB-based program for perfect IR detection. In comparison with other existing tools, our program demonstrates a high accuracy in detecting nested and overlapping IRs. |
Year | DOI | Venue |
|---|---|---|
2014 | 10.1093/bioinformatics/btt651 | BIOINFORMATICS |
Field | DocType | Volume |
Genome,MATLAB,Source code,Computer science,Algorithm,Inverted repeat,Software,DNA sequencing,Bioinformatics,Palindromic sequence,DNA replication | Journal | 30 |
Issue | ISSN | Citations |
6 | 1367-4803 | 3 |
PageRank | References | Authors |
0.46 | 1 | 4 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Sutharzan Sreeskandarajan | 1 | 3 | 0.46 |
| Michelle M Flowers | 2 | 3 | 0.46 |
| John E. Karro | 3 | 24 | 4.40 |
| Chun Liang | 4 | 31 | 6.53 |