Name
Abstract | ||
|---|---|---|
L1 Base is a dedicated database containing putatively active LINE-1 (L1) insertions residing in human and rodent genomes that are as follows: (i) intact in the two open reading frames (ORFs), full-length L1s (FLI-L1s) and (ii) intact ORF2 but disrupted ORF1 (ORF2-L1s). In addition, due to their regulatory potential, the full-length (>6000 bp) non-intact L1s (FLnI-L1s) were also included in the database. Application of a novel annotation methodology, L1Xplorer, allowed in-depth annotation of functional sequence features important for L1 activity, such as transcription factor binding sites and amino acid residues. The L1 Base is available online at http://l1base.molgen.mpg.de. In addition, the data stored in the database can be accessed from the Ensembl web browser via a DAS service (I1das.molgen.mpg.de:8080/das). |
Year | DOI | Venue |
|---|---|---|
2005 | 10.1093/nar/gki044 | NUCLEIC ACIDS RESEARCH |
Keywords | Field | DocType |
genomics,transcription factors,open reading frames,binding sites | Genome,LINE-1 Elements,Annotation,DNA binding site,Biology,Ensembl,Genomics,Open reading frame,ORFS,Genetics | Journal |
Volume | Issue | ISSN |
33 | Database issue | 0305-1048 |
Citations | PageRank | References |
5 | 0.66 | 2 |
Authors | ||
3 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Tobias Penzkofer | 1 | 15 | 3.49 |
| Thomas Dandekar | 2 | 411 | 23.17 |
| Tomasz Zemojtel | 3 | 15 | 2.34 |