Abstract | ||
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Published information on contrast detection threshold is based primarily on research using a location-known methodology. In previous work on testing the Digital Imaging and Communications in Medicine (DICOM) Grayscale Standard Display Function (GSDF) for perceptual linearity, this research group used a location-unknown methodology to more closely reflect clinical practice. A high false-positive rate resulted in a high variance leading to the conclusion that the impact on results of employing a location-known methodology needed to be explored. Fourteen readers reviewed two sets of simulated mammographic background images, one with the location-unknown and one with the location-known methodology. The results of the reader study were analyzed using Reader Operating Characteristic (ROC) methodology and a paired t test. Contrast detection threshold was analyzed using contingency tables. No statistically significant difference was found in GSDF testing, but a highly statistical significant difference (p value <0.0001) was seen in the ROC (AUC) curve between the location-unknown and the location-known methodologies. Location-known methodology not only improved the power of the GSDF test but also affected the contrast detection threshold which changed from +3 when the location was unknown to +2 gray levels for the location-known images. The selection of location known versus unknown in experimental design must be carefully considered to ensure that the conclusions of the experiment reflect the study's objectives. |
Year | DOI | Venue |
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2013 | 10.1007/s10278-013-9589-4 | J. Digital Imaging |
Keywords | Field | DocType |
Image perception,contrast threshold,GSDF,ROC,SKE,LKE | Computer vision,Mammography,DICOM,Computer science,p-value,Clinical Practice,Linearity,Contingency table,Artificial intelligence,Statistics,Student's t-test,Analysis of variance | Journal |
Volume | Issue | ISSN |
26 | 6 | 1618-727X |
Citations | PageRank | References |
0 | 0.34 | 2 |
Authors | ||
8 |
Name | Order | Citations | PageRank |
---|---|---|---|
David L. Leong | 1 | 2 | 0.86 |
Louise Rainford | 2 | 2 | 0.86 |
Tamara Miner Haygood | 3 | 14 | 2.98 |
Gary J. Whitman | 4 | 43 | 5.76 |
William R. Geiser | 5 | 4 | 1.61 |
Beatriz E. Adrada | 6 | 2 | 0.75 |
Lumarie Santiago | 7 | 0 | 0.68 |
Patrick C. Brennan | 8 | 4 | 12.71 |