Title
Fast and Adaptive Variable Order Markov Chain Construction
Abstract
Variable order Markov chains (VOMCs) are a flexible class of models that extend the well-known Markov chains. They have been applied to a variety of problems in computational biology, e.g. protein family classification. A linear time and space construction algorithm has been published in 2000 by Apostolico and Bejerano. However, neither a report of the actual running time nor an implementation of it have been published since. In this paper we use the lazy suffix tree and the enhanced suffix array to improve upon the algorithm of Apostolico and Bejerano. We introduce a new software which is orders of magnitude faster than current tools for building VOMCs, and is suitable for large scale sequence analysis.
Year
DOI
Venue
2008
10.1007/978-3-540-87361-7_26
WABI
Keywords
Field
DocType
variable order markov chain,flexible class,chain construction,lazy suffix tree,current tool,enhanced suffix array,adaptive variable order markov,well-known markov chain,linear time,computational biology,space construction algorithm,large scale sequence analysis,markov chain,sequence analysis,computer science,g protein
Computer science,Theoretical computer science,Software,Generalized suffix tree,Suffix tree,Time complexity,Combinatorics,Markov chain,Algorithm,Suffix array,Variable-order Markov model,Bioinformatics,Compressed suffix array
Conference
Volume
ISSN
Citations 
5251
0302-9743
9
PageRank 
References 
Authors
0.49
24
6
Name
Order
Citations
PageRank
Marcel H Schulz124024.03
David Weese225217.79
Tobias Rausch326218.00
Andreas Döring419519.38
Knut Reinert51020105.87
Martin Vingron61754298.16