Title
Patterns of cortical thickness and surface area in early Parkinson's disease.
Abstract
Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder diagnosed on the basis of motor symptoms, but that also includes cognitive and visuo-spatial deficits. Though PD is known to initially affect subcortical regions, the cortex also exhibits neuronal loss in the course of the disease as post mortem studies have shown. So far, PD-related pattern of cortical damage remains unclear, because of disease-caused heterogeneity, and also in part because of methodological issues such as the limitations of Voxel Based Morphometry. Here corticometry was used, a technique that decouples local surface from thickness, to obtain a better picture of PD corticomorphometric patterns.
Year
DOI
Venue
2011
10.1016/j.neuroimage.2010.12.043
NeuroImage
Keywords
Field
DocType
Parkinson's disease,Cingulate cortex,Magnetic resonance imaging,Corticometry,Aging,Supplementary motor area
SMA*,Cortex (botany),Cingulate cortex,Developmental psychology,Parkinson's disease,Neuroscience,Psychology,Cognitive psychology,Supplementary motor area,Voxel-based morphometry,Cognition,Magnetic resonance imaging
Journal
Volume
Issue
ISSN
55
2
1053-8119
Citations 
PageRank 
References 
5
0.59
8
Authors
7
Name
Order
Citations
PageRank
Thomas Jubault150.59
J Gagnon2198.17
Sherif Karama3655.15
Alain Ptito4162.48
Anne-Louise Lafontaine550.59
Alan C. Evans63045574.95
Oury Monchi7328.88