Title
Spatial Mixture Modelling For The Joint Detection-Estimation Of Brain Activity In Fmri
Abstract
Within-subject analysis in event-related functional Magnetic Resonance Imaging (fMRI) first relies on (i) a detection step to localize which parts of the brain are activated by a given stimulus type, and then on (ii) an estimation step to recover the temporal dynamics of the brain response. Recently, we have proposed a Bayesian detection-estimation approach that jointly addresses (i)-(ii) [1]. This approach provides both a spatial activity map and an estimate of brain dynamics. Here, we consider an extension that accounts for spatial correlation using a spatial mixture model (SMM) based on a binary Markov random field. It allows us to avoid any spatial smoothing of the data prior to the statistical analysis. Our simulation results support that SMM gives a better control of false positive (specificity) and false negative (sensitivity) rates than independent mixtures.
Year
DOI
Venue
2007
10.1109/ICASSP.2007.366682
2007 IEEE INTERNATIONAL CONFERENCE ON ACOUSTICS, SPEECH, AND SIGNAL PROCESSING, VOL I, PTS 1-3, PROCEEDINGS
Keywords
Field
DocType
Bayes procedures, biomedical signal detection, magnetic resonance imaging
Query optimization,Data mining,Data security,Relational database,Computer science,Range query (data structures),Sargable,View,Security analysis,Database,Cloud computing
Conference
ISSN
Citations 
PageRank 
1520-6149
10
1.11
References 
Authors
5
3
Name
Order
Citations
PageRank
Thomas Vincent132027.52
Philippe Ciuciu245250.82
Idier, J.356659.01