Name
Title | ||
|---|---|---|
Combined experimental and computational approaches to study the regulatory elements in eukaryotic genes. |
Abstract | ||
|---|---|---|
The recognition of transcription factor binding sites (TFBSs) is the first step on the way to deciphering the DNA regulatory code. There is a large variety of experimental approaches providing information on TFBS location in genomic sequences. Many computational approaches to TFBS recognition based on the experimental data obtained are available, each having its own advantages and shortcomings. This article provides short review of approaches to computational recognition of TFBS in genomic sequences and methods of experimental verification of predicted sites. We also present a case study of the interplay between experimental and theoretical approaches to the successful prediction of Steroidogenic Factor I (SFI). |
Year | DOI | Venue |
|---|---|---|
2007 | 10.1093/bib/bbm027 | BRIEFINGS IN BIOINFORMATICS |
Keywords | Field | DocType |
genome annotation,transcription factor binding site recognition,computer-assisted and experimental methods,sequence training-samples | Genome,Data mining,Gene,DNA binding site,Biology,Genome project,Experimental data,Bioinformatics | Journal |
Volume | Issue | ISSN |
8 | 4 | 1467-5463 |
Citations | PageRank | References |
5 | 0.62 | 26 |
Authors | ||
10 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Nikolay A. Kolchanov | 1 | 470 | 105.75 |
| Tatyana I. Merkulova | 2 | 114 | 12.70 |
| Elena V. Ignatieva | 3 | 104 | 25.66 |
| Elena A. Ananko | 4 | 137 | 24.92 |
| Dmitry Oshchepkov | 5 | 24 | 3.95 |
| Victor G. Levitsky | 6 | 57 | 7.52 |
| Gennady V. Vasiliev | 7 | 14 | 3.03 |
| Nataly V. Klimova | 8 | 5 | 0.96 |
| Vasily M. Merkulov | 9 | 5 | 0.96 |
| T. Charles Hodgman | 10 | 960 | 187.36 |