Abstract | ||
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Petri net has been employed for modeling metabolic pathways as well as signal transduction pathways and gene regulatory networks. The purpose of this paper is to introduce an extension of Petri net called hybrid functional Petri net (HFPN) which allows us to model biopathways naturally and effectively. The method for creating biopathways with HFPN is demonstrated through a well-known biopathway example "lac operon gene regulatory mechanism and glycolytic pathway." In order to evaluate this biopathway model, simulations of five mutants of the lac operon are carried out by Genomic Object Net which is a biopathway simulator based on the HFPN architecture. The software Genomic Object Net and the HFPN files presented in this paper can be downloaded from http://www.GenomicObject.Net/. |
Year | DOI | Venue |
---|---|---|
2003 | 10.1007/3-540-44919-1_2 | ICATPN |
Keywords | Field | DocType |
software genomic object,hfpn architecture,biopathway model,regulatory mechanism,gene regulatory network,lac operon,well-known biopathway example,biopathway simulator,lac operon gene,towards biopathway modeling,genomic object,petri net,metabolic pathway,modeling and simulation,signal transduction pathway | lac operon,Petri net,Computer science,Modeling and simulation,LAC operon gene,Software,Transmission protocol,Gene regulatory network,Distributed computing | Conference |
Volume | ISSN | ISBN |
2679 | 0302-9743 | 3-540-40334-5 |
Citations | PageRank | References |
19 | 1.22 | 10 |
Authors | ||
5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Hiroshi Matsuno | 1 | 257 | 33.71 |
Sachie Fujita | 2 | 70 | 6.73 |
Atsushi Doi | 3 | 160 | 11.23 |
Masao Nagasaki | 4 | 368 | 26.22 |
Satoru Miyano | 5 | 2406 | 250.71 |