Title
An analysis pipeline for the inference of protein-protein interaction networks
Abstract
We present a platform for the reconstruction of protein-protein interaction networks inferred from Mass Spectrometry (MS) bait-prey data. The Software Environment for Biological Network Inference (SEBINI), an environment for the deployment of network inference algorithms that use high-throughput data, forms the platform core. Among the many algorithms available in SEBINI is the Bayesian Estimator of Probabilities of Protein-Protein Associations (BEPro3) algorithm, which is used to infer interaction networks from such MS affinity isolation data. Also, the pipeline incorporates the Collective Analysis of Biological Interaction Networks (CABIN) software. We have thus created a structured workflow for protein-protein network inference and supplemental analysis.
Year
DOI
Venue
2009
10.1504/IJDMB.2009.029204
IJDMB
Keywords
DocType
Volume
network inference pipeline, protein-protein interactions, networks, MS, mass spectrometry, Bayesian
Journal
3
Issue
ISSN
Citations 
4
1748-5673
3
PageRank 
References 
Authors
0.44
7
16