Title
Integrating sequence and structural biology with DAS.
Abstract
The Distributed Annotation System (DAS) is a network protocol for exchanging biological data. It is frequently used to share annotations of genomes and protein sequence.Here we present several extensions to the current DAS 1.5 protocol. These provide new commands to share alignments, three dimensional molecular structure data, add the possibility for registration and discovery of DAS servers, and provide a convention how to provide different types of data plots. We present examples of web sites and applications that use the new extensions. We operate a public registry of DAS sources, which now includes entries for more than 250 distinct sources.Our DAS extensions are essential for the management of the growing number of services and exchange of diverse biological data sets. In addition the extensions allow new types of applications to be developed and scientific questions to be addressed. The registry of DAS sources is available at http://www.dasregistry.org.
Year
DOI
Venue
2007
10.1186/1471-2105-8-333
BMC Bioinformatics
Keywords
Field
DocType
bioinformatics,three dimensional,internet,sequence analysis,systems integration,network protocol,computational biology,algorithms,biological data,database management systems,structural biology,protein sequence,molecular structure,microarrays
Genome,Biological data,Structural alignment,Annotation,Protein sequencing,Computer science,Structural biology,SOAP,Computational biology,Bioinformatics,Sequence analysis
Journal
Volume
Issue
ISSN
8
1
1471-2105
Citations 
PageRank 
References 
47
5.67
24
Authors
6
Name
Order
Citations
PageRank
Andreas Prlic190793.82
T Down250156.90
Eugene Kulesha3777110.57
Robert D Finn44179636.56
Andreas Kähäri5755122.60
Tim J. P. Hubbard61898332.55