Name
Title | ||
|---|---|---|
Motion correction of multi-frame PET data in neuroreceptor mapping: simulation based validation. |
Abstract | ||
|---|---|---|
Patient motion during positron emission tomography scanning can affect the accuracy of the data analysis in two ways: 1) movement occurring during emission data acquisition alters the time activity curves (TACs), measured at a voxel or region of interest (ROI), and hence introduces errors in the parameter estimates derived from kinetic modeling; 2) emission–transmission mismatches introduce errors during attenuation and scatter correction, and hence in the radioactivity distribution estimates for each time frame of the scan. With the aim of designing an algorithm-based frame realignment method, we first conducted investigations that aimed at optimizing the parameters of a coregistration method, such as the choice of the target volume and the similarity criterion. Based on these results we designed a novel frame realignment strategy in a multi-step algorithm using uncorrected reconstructed images, cross-correlation similarity criteria for the determination of inter-frame motion parameters and emission-transmission mismatch for each frame. Features and validation results are reported here based on a multi-subject simulated [11C]raclopride dynamic PET scan database incorporating intra-frame movements of various magnitudes and with various times of occurrence. Performances of the proposed algorithm were evaluated at regional and voxel-based level for binding potential parametric images. |
Year | DOI | Venue |
|---|---|---|
2009 | 10.1016/j.neuroimage.2009.05.052 | NeuroImage |
Keywords | Field | DocType |
PET,Patient motion correction,Inter frame registration,Binding potential,Brain,Simulation | Voxel,Computer science,Cognitive psychology,Positron emission tomography,Artificial intelligence,Motion correction,Computer vision,Data acquisition,Algorithm,Parametric statistics,Attenuation,Region of interest,Binding potential | Journal |
Volume | Issue | ISSN |
47 | 4 | 1053-8119 |
Citations | PageRank | References |
8 | 1.00 | 8 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Nicolas Costes | 1 | 47 | 8.25 |
| Alain Dagher | 2 | 54 | 9.26 |
| Kevin Larcher | 3 | 11 | 1.91 |
| Alan C. Evans | 4 | 3045 | 574.95 |
| D. Louis Collins | 5 | 3915 | 403.90 |
| Anthonin Reilhac | 6 | 50 | 8.20 |