Paper Info
Title
Intensive in vitro experiments of implementing and executing finite automata in test tube
Abstract
We report our intensive in vitro experiments in which we have implemented and executed several finite-state automata in test tube. First, we employ the length-encoding technique proposed and presented in [4, 3] to implement finite automata in test tube. In the length-encoding method, the states and state transition functions of a target finite automaton are effectively encoded into DNA sequences, a computation (accepting) process of finite automata is accomplished by self-assembly of encoded complementary DNA strands, and the acceptance of an input string is determined by the detection of a completely hybridized double-strand DNA. Second, we design and develop practical laboratory protocols which combine several in vitro operations such as annealing, ligation, PCR, and streptavidin-biotin bonding to execute in vitro finite automata based on the length-encoding technique. We have carried laboratory experiments on various finite automata of from 2 states to 6 states for several input strings. To our knowledge, this is the first in vitro experiments that have succeeded to execute 6-states automaton in test tube.
Year
DOI
Venue
2005
10.1007/11753681_15
DNA
Keywords
Field
DocType
vitro experiment,finite automaton,dna sequence,vitro operation,target finite automaton,input string,length-encoding technique,test tube,vitro finite automaton,various finite automaton,finite automata,state transition,self assembly,finite state automata
Computer science,Automaton,Algorithm,Finite-state machine,Timed automaton,String (computer science),Computation
Conference
Volume
ISSN
ISBN
3892
0302-9743
3-540-34161-7
Citations 
PageRank 
References 
3
0.59
2
Authors
2
Name
Order
Citations
PageRank
Junna Kuramochi130.59
Yasubumi Sakakibara276962.91