Title
IRView: a database and viewer for protein interacting regions.
Abstract
Protein-protein interactions (PPIs) are mediated through specific regions on proteins. Some proteins have two or more protein interacting regions (IRs) and some IRs are competitively used for interactions with different proteins. IRView currently contains data for 3417 IRs in human and mouse proteins. The data were obtained from different sources and combined with annotated region data from InterPro. Information on non-synonymous single nucleotide polymorphism sites and variable regions owing to alternative mRNA splicing is also included. The IRView web interface displays all IR data, including user-uploaded data, on reference sequences so that the positional relationship between IRs can be easily understood. IRView should be useful for analyzing underlying relationships between the proteins behind the PPI networks.
Year
DOI
Venue
2012
10.1093/bioinformatics/bts289
BIOINFORMATICS
Keywords
Field
DocType
internet,alternative splicing,proteins
Biology,Alternative splicing,RNA splicing,Single-nucleotide polymorphism,Bioinformatics,InterPro
Journal
Volume
Issue
ISSN
28
14
1367-4803
Citations 
PageRank 
References 
2
0.35
7
Authors
10