Title
NIRS study of cerebral oxygenation and hemodynamics in neonate at birth.
Abstract
To study the changes of cerebral oxygenation and hemodynamics in normal neonates at 2-5 min post-birth and understand the effects of pregnancy-induced hypertension (PIH) upon cerebral oxygenation and hemodynamics in newborn neonates. The near infrared spectroscopy (NIRS) was employed to measure the absolute quantity of brain tissue oxygen saturation (rSO2) in newborn neonates and the changes of concentrations of deoxyhemoglobin (Hb) and oxygenation hemoglobin (HbO2) with time relative to initial values to further obtain the changes of total hemoglobin (tHb) and cerebral perfusion (denoted by HbD). In normal neonates at 2-5 min post-birth, rSO2 increased while tHb remained relatively stable and HbD increased. In neonates born of PIH mothers at 3-5 min post-birth, the changes of tHb were markedly higher than those in the normal infants, p<0.05; at 2-5 min post-birth, the changes were markedly lower than the normal term infants. We concluded that NIRS can detect the changes of cerebral oxygenation and blood flow in a non-invasive and effective way.
Year
DOI
Venue
2011
10.1109/IEMBS.2011.6090289
EMBC
Keywords
Field
DocType
pregnancy induced hypertension effects,near infrared spectroscopy,paediatrics,medical disorders,neonatal cerebral oxygenation,haemorheology,biomedical measurement,nirs,spectrochemical analysis,biochemistry,pih,brain,cerebral perfusion,deoxyhemoglobin concentration changes,infrared spectroscopy,neonatal cerebral hemodynamics,total hemoglobin,brain tissue oxygen saturation,haemodynamics,blood,spectroscopy,blood flow,oxygen saturation,pediatrics,hemodynamics
Hemoglobin,Hemodynamics,Blood flow,Total hemoglobin,Oxygen saturation,Anesthesia,Oxygenation,Cerebral perfusion pressure,Medicine,Brain tissue
Conference
Volume
Issue
ISSN
2011
null
1557-170X
ISBN
Citations 
PageRank 
978-1-4244-4122-8
0
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
Xinlin Hou101.01
Ding Haiyan242.61
Yichao Teng300.68
Congle Zhou400.34
Dandan Zhang500.34