Name
Title | ||
|---|---|---|
Clinical doses of atomoxetine significantly occupy both norepinephrine and serotonin transports: Implications on treatment of depression and ADHD. |
Abstract | ||
|---|---|---|
•We examine the in vivo selectivity of atomoxetine (ATX) with PET.•[11C]MRB and [11C]AFM were used to evaluate ATX IC50 values for NET & SERT.•ATX at clinically relevant doses greatly occupies both NET and SERT.•ATX for treatment of depression and ADHD may be more complex than current thinking.•The implications on the therapeutic mechanisms of ATX are discussed. |
Year | DOI | Venue |
|---|---|---|
2014 | 10.1016/j.neuroimage.2013.08.001 | NeuroImage |
Keywords | Field | DocType |
Atomoxetine,Attention deficit hyperactivity disorder,Depression,Norepinephrine transporter,Serotonin transporter,Positron emission tomography | Atomoxetine,Serotonin,DASB,Internal medicine,Psychology,Serotonin transporter,Fluoxetine,Free fraction,Norepinephrine transporter,Endocrinology,Placebo | Journal |
Volume | ISSN | Citations |
86 | 1053-8119 | 0 |
PageRank | References | Authors |
0.34 | 1 | 11 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Yu-Shin Ding | 1 | 26 | 6.54 |
| Mika Naganawa | 2 | 41 | 8.49 |
| Jean-Dominique Gallezot | 3 | 5 | 4.75 |
| Nabeel Nabulsi | 4 | 3 | 4.12 |
| Shu-Fei Lin | 5 | 4 | 4.57 |
| Jim Ropchan | 6 | 0 | 2.03 |
| David Weinzimmer | 7 | 5 | 3.47 |
| Timothy J. McCarthy | 8 | 7 | 2.24 |
| Richard E. Carson | 9 | 71 | 27.03 |
| Yiyun Huang | 10 | 2 | 3.84 |
| Marc Laruelle | 11 | 24 | 7.53 |