Paper Info
Title
Seva 2.0: An Update Of The Standard European Vector Architecture For De-/Re-Construction Of Bacterial Functionalities
Abstract
The Standard European Vector Architecture 2.0 database (http://seva.cnb.csic.es) is an improved and expanded version of the platform released in 2013 (doi: 10.1093/nar/gks1119) aimed at assisting the choice of optimal genetic tools for de-constructing and re-constructing complex prokaryotic phenotypes. By adopting simple compositional rules, the SEVA standard facilitates combinations of functional DNA segments that ease both the analysis and the engineering of diverse Gram-negative bacteria for fundamental or biotechnological purposes. The large number of users of the SEVA-DB during its first two years of existence has resulted in a valuable feedback that we have exploited for fixing DNA sequence errors, improving the nomenclature of the SEVA plasmids, expanding the vector collection, adding new features to the web interface and encouraging contributions of materials from the community of users. The SEVA platform is also adopting the Synthetic Biology Open Language (SBOL) for electronic-like description of the constructs available in the collection and their interfacing with genetic devices developed by other Synthetic Biology communities. We advocate the SEVA format as one interim asset for the ongoing transition of genetic design of microorganisms from being a trial-and-error endeavor to become an authentic engineering discipline.
Year
DOI
Venue
2015
10.1093/nar/gku1114
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Architecture,Biology,Interfacing,Genetics,Synthetic biology,The Internet
Journal
43
Issue
ISSN
Citations 
D1
0305-1048
1
PageRank 
References 
Authors
0.35
1
5
Name
Order
Citations
PageRank
Esteban Martínez-García110.35
Tomás Aparicio210.35
Ángel Goñi Moreno3195.70
Sofía Fraile410.69
Víctor de Lorenzo571.32