Title
Evaluating the impacts of vaccination, antiviral treatment and school closure on H1N1 influenza epidemic
Abstract
Multi-objective simulation optimization was performed to synergistically investigate the cost and benefits of the most commonly-used strategies for H1N1 epidemic mitigation: vaccination, antiviral treatment, and school closure. By simultaneously considering the three intervention strategies, this study leads to findings that supplement those in the existing work, and provides additional insights regarding intervention decision making. Specifically, our investigation suggests that different vaccine prioritization strategies, the age-based vs. ACIP (Advisory Committee on Immunization Practices) recommendation, be implemented depending on vaccine availability; individual school closure policies are favored over their global counterparts, at least when both vaccination and antiviral treatment are implemented with relatively plentiful medicine supply. The trade-offs of cost and benefits of the intervention strategies were investigated, and can be used to support relevant decision making.
Year
DOI
Venue
2014
10.1109/WSC.2014.7019999
Winter Simulation Conference
Keywords
Field
DocType
diseases,acip recommendation,decision making,h1n1 epidemic mitigation,vaccination,h1n1 influenza epidemic,multiobjective simulation optimization,antiviral treatment,school closure,plentiful medicine supply,vaccine prioritization strategies,advisory committee-on-immunization practice recommendation
Computer science,Simulation,Vaccination,Prioritization,H1N1 influenza,Cost–benefit analysis
Conference
ISSN
ISBN
Citations 
0891-7736
978-1-4673-9741-4
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Junhai Cao100.34
Feng Yang2477.21
Zongyu Geng300.34
Xiaofei Shi400.34