Title
Exploring functional brain dynamics via a Bayesian connectivity change point model
Abstract
Multiple recent neuroimaging studies have demonstrated that the human brain's function undergoes remarkable temporal dynamics. However, quantitative characterization and modeling of such functional dynamics have been rarely explored. To fill this gap, we presents a novel Bayesian connectivity change point model (BCCPM), to analyze the joint probabilities among the nodes of brain networks between different time periods and statistically determine the boundaries of temporal blocks to estimate the change points. Intuitively, the determined change points represent the transitions of functional interaction patterns within the brain networks and can be used to investigate temporal functional brain dynamics. The BCCPM has been evaluated and validated by synthesized data. Also, the BCCPM has been applied to a real block-design task-based fMRI dataset and interesting results were obtained.
Year
DOI
Venue
2014
10.1109/ISBI.2014.6867942
ISBI
Keywords
DocType
ISSN
BCCPM,belief networks,temporal blocks,block-design task-based fMRI dataset,graph model,biomedical MRI,brain,brain networks,temporal functional brain dynamics,Bayesian connectivity change point model,change point detection,functional interaction patterns,neuroimaging,medical image processing,fMRI
Conference
1945-7928
Citations 
PageRank 
References 
6
0.65
10
Authors
11
Name
Order
Citations
PageRank
Zhichao Lian1121.92
Xiang Li212615.50
Jianchuan Xing360.65
Jinglei Lv420526.70
Xi Jiang531137.88
Dajiang Zhu632036.72
Shu Zhang712613.64
Jiansong Xu8202.07
Marc N. Potenza960.65
Tianming Liu101033112.95
Jing Zhang118410.71