Title
Parallel Biological Sequence Comparison on Heterogeneous High Performance Computing Platforms with BSP++
Abstract
Biological Sequence Comparison is an important operation in Bioinformatics that is often used to relate organisms. Smith and Waterman proposed an exact algorithm (SW) that compares two sequences in quadratic time and space. Due to high computing and memory requirements, SW is usually executed on HPC platforms such as multicore clusters and CellBEs. Since HPC architectures exhibit very different hardware characteristics, porting an application between them is an error-prone time-consuming task. BSP++ is an implementation of BSP that aims to reduce the effort to write parallel code. In this paper, we propose and evaluate a parallel BSP++ strategy to execute SW in multiple platforms like MPI, OpenMP, MPI/OpenMP, CellBE and MPI/CellBE. The results obtained with real DNA sequences show that the performance of our versions is comparable to the ones in the literature, evidencing the appropriateness and flexibility of our approach.
Year
DOI
Venue
2011
10.1109/SBAC-PAD.2011.16
Computer Architecture and High Performance Computing
Keywords
Field
DocType
bioinformatics,parallel processing,CellBE,DNA sequences,HPC platform,MPI,OpenMP,bioinformatics,bulk synchronous parallel model,heterogeneous high performance computing,parallel BSP++,parallel biological sequence comparison
Object-oriented modeling,Exact algorithm,Supercomputer,Computer science,Parallel computing,Parallel processing,Porting,Time complexity,Multi-core processor
Conference
ISSN
ISBN
Citations 
1550-6533
978-1-4577-2050-5
1
PageRank 
References 
Authors
0.38
12
4
Name
Order
Citations
PageRank
Khaled Hamidouche118019.45
Fernando M. Mendonca210.38
Joel Falcou39611.30
Daniel Etiemble430042.43