Abstract | ||
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Radio-frequency ablation (RFA) has been used in liver surgery to minimize blood loss during tissue division. However, the current RFA tissue division method lacks an effective way of determining the stoppage of blood flow. There is limitation on the current state-of-the-art laser Doppler flow sensor due to its small sensing area. A new technique was proposed to use bioimpedance for blood flow sensing. This paper discusses a new geometrical multiscale model of the liver bioimpedance incorporating blood flow impedance. This model establishes correlation between the physical tissue structure and bioimpedance measurement. The basic Debye structure within a multilevel framework is used in the model to account for bioimpedance dispersion. This dispersion is often explained by the Cole-Cole model that includes a constant phase element without physical explanation. Our model is able to account for reduced blood flow in its output with changes in permittivity in gamma dispersion that is mainly due to the polarization of water molecules. This study demonstrates the potential of a multiscale model in determining the stoppage of blood flow during surgery. |
Year | DOI | Venue |
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2012 | 10.1109/TBME.2012.2190511 | IEEE transactions on bio-medical engineering |
Keywords | Field | DocType |
radiation therapy,radio-frequency ablation (rfa),blood flow,geometrical multiscale model,constant phase element,liver tissue,cole-cole model,bioimpedance,debye structure,dispersion,debye temperature,rfa tissue division method,blood flow sensing,radio-frequency ablation,biothermics,multiscale model,bioelectric phenomena,blood flow impedance,liver,liver surgery,permittivity,bioimpedance dispersion,biological tissues,gamma dispersion,electric impedance imaging,surgery,haemodynamics | Hemodynamics,Biomedical engineering,Dispersion (optics),Permittivity,Blood flow,Laser Doppler velocimetry,Debye,Computer science,Debye model,Constant phase element | Journal |
Volume | Issue | ISSN |
59 | 6 | 1558-2531 |
Citations | PageRank | References |
1 | 0.37 | 1 |
Authors | ||
4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Wei-Hsuang Huang | 1 | 1 | 0.37 |
Chee-Kong Chui | 2 | 245 | 38.34 |
Swee-Hin Teoh | 3 | 15 | 3.41 |
Stephen Chang | 4 | 134 | 8.90 |