Title
Sample preparation for droplet-based microfluidics
Abstract
Sample preparation plays an essential role in most biochemical reactions. Raw reactants are diluted to solutions with desirable concentration values in this process. In this paper, a survey of existing techniques addressing sample preparation on digital microfluidic biochips (DMFBs) is given. The fundamentals of DMFBs are introduced first. Next, we explain how dilution operations are performed on DMFBs and how the constraint on mixing models comes due to the DMFB architecture limit. Then, we divide the existing techniques into four groups according to the count of target concentration values as well as the number of different reactant types, and briefly introduce selected major research works in each category.
Year
DOI
Venue
2014
10.1109/ISICIR.2014.7029560
ISIC
Keywords
Field
DocType
biomems,biochemistry,biological techniques,lab-on-a-chip,microfluidics,dmfb architecture limit,biochemical reactions,digital microfluidic biochips,dilution operations,droplet-based microfluidics,mixing models,raw reactants,sample preparation,target concentration values,biochip,digital microfluidic biochip (dmfb),dilution,lab-on-a-chip (loc),optimization,minimization,algorithm design and analysis
Process engineering,Nanotechnology,Biochip,Algorithm design,Microfluidics,Sample preparation,Biochemical reactions,Engineering,Droplet-based microfluidics
Conference
ISSN
Citations 
PageRank 
2325-0631
0
0.34
References 
Authors
14
2
Name
Order
Citations
PageRank
Juinn-Dar Huang127027.42
Chia-Hung Liu21699.57