Title
Control synthesis for the flow-based microfluidic large-scale integration biochips
Abstract
In this paper we are interested in flow-based microfluidic biochips, which are able to integrate the necessary functions for biochemical analysis on-chip. In these chips, the flow of liquid is manipulated using integrated microvalves. By combining several microvalves, more complex units, such as micropumps, mixers, and multiplexers, can be built. In this paper we propose, for the first time to our knowledge, a top-down control synthesis framework for the flow-based biochips. Starting from a given biochemical application and a biochip architecture, we synthesize the control logic that is used by the biochip controller to automatically execute the biochemical application. We also propose a control pin count minimization scheme aimed at efficiently utilizing chip area, reducing macro-assembly around the chip and enhancing chip scalability. We have evaluated our approach using both real-life applications and synthetic benchmarks.
Year
DOI
Venue
2013
10.1109/ASPDAC.2013.6509597
Design Automation Conference
Keywords
Field
DocType
lab-on-a-chip,microfluidics,micropumps,microvalves,mixers (circuits),multiplexing equipment,biochemical analysis on-chip,biochip controller,control logic,control pin count minimization scheme,control synthesis,flow-based microfluidic large-scale integration biochips,micropumps,microvalves,mixers,multiplexers
Control theory,Biochip,Computer science,Microfluidics,Chip,Multiplexer,Electronic engineering,Control logic,Lab-on-a-chip,Scalability
Conference
ISSN
ISBN
Citations 
2153-6961
978-1-4673-3029-9
17
PageRank 
References 
Authors
1.22
4
4
Name
Order
Citations
PageRank
Wajid Hassan Minhass1171.22
Paul Pop289968.16
Jan Madsen357656.90
Tsung-Yi Ho4171.22