Title
A joint estimation detection of Glaucoma progression in 3D spectral domain optical coherence tomography optic nerve head images.
Abstract
Glaucoma is an ocular disease characterized by distinctive changes in the optic nerve head (ONH) and visual field. Glaucoma can strike without symptoms and causes blindness if it remains without treatment. Therefore, early disease detection is important so that treatment can be initiated and blindness prevented. In this context, important advances in technology for non-invasive imaging of the eye have been made providing quantitative tools to measure structural changes in ONH topography, an essential element for glaucoma detection and monitoring. 3D spectral domain optical coherence tomography (SD-OCT), an optical imaging technique, has been commonly used to discriminate glaucomatous from healthy subjects. In this paper, we present a new framework for detection of glaucoma progression using 3D SD-OCT images. In contrast to previous works that the retinal nerve fiber layer (RNFL) thickness measurement provided by commercially available spectral-domain optical coherence tomograph, we consider the whole 3D volume for change detection. To integrate a priori knowledge and in particular the spatial voxel dependency in the change detection map, we propose the use of the Markov Random Field to handle a such dependency. To accommodate the presence of false positive detection, the estimated change detection map is then used to classify a 3D SDOCT image into the "non-progressing" and "progressing" glaucoma classes, based on a fuzzy logic classifier. We compared the diagnostic performance of the proposed framework to existing methods of progression detection.
Year
DOI
Venue
2014
10.1117/12.2041980
Proceedings of SPIE
Keywords
Field
DocType
Glaucoma,Markov field,change detection,fuzzy logic classifier
Voxel,Computer vision,Glaucoma,Optical coherence tomography,Change detection,Nerve fiber layer,Optics,Coherence (physics),Artificial intelligence,Visual field,Optic nerve,Physics
Conference
Volume
ISSN
Citations 
9035
0277-786X
1
PageRank 
References 
Authors
0.36
3
4
Name
Order
Citations
PageRank
Akram Belghith1224.99
Christopher Bowd221.09
Weinreb Robert N310.36
Linda M Zangwill421.09