Paper Info
Title
NaviCell Web Service for network-based data visualization.
Abstract
Data visualization is an essential element of biological research, required for obtaining insights and formulating new hypotheses on mechanisms of health and disease. NaviCell Web Service is a tool for network-based visualization of 'omics' data which implements several data visual representation methods and utilities for combining them together. NaviCell Web Service uses Google Maps and semantic zooming to browse large biological network maps, represented in various formats, together with different types of the molecular data mapped on top of them. For achieving this, the tool provides standard heatmaps, barplots and glyphs as well as the novel map staining technique for grasping largescale trends in numerical values (such as whole transcriptome) projected onto a pathway map. The web service provides a server mode, which allows automating visualization tasks and retrieving data from maps via RESTful (standard HTTP) calls. Bindings to different programming languages are provided (Python and R). We illustrate the purpose of the tool with several case studies using pathway maps created by different research groups, in which data visualization provides new insights into molecular mechanisms involved in systemic diseases such as cancer and neurodegenerative diseases.
Year
DOI
Venue
2015
10.1093/nar/gkv450
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Glyph,Data visualization,Biology,Information retrieval,Information visualization,Visualization,Biological network,Bioinformatics,Genetics,Web service,Python (programming language),The Internet
Journal
43
Issue
ISSN
Citations 
W1
0305-1048
7
PageRank 
References 
Authors
0.44
13
7
Name
Order
Citations
PageRank
Eric Bonnet170.44
Eric Viara270.44
Inna Kuperstein370.44
Laurence Calzone470.78
David P A Cohen5141.06
Emmanuel Barillot6950165.00
A Zinovyev7273.14