Name
Abstract | ||
|---|---|---|
Q-ball imaging (QBI) is a diffusion imaging technique that provides unique microstructural information and outperforms diffusion tensor imaging (DTI) in areas of fiber crossings. The generalized fractional anisotropy (GFA) is a widely accepted quantitative measure of fiber integrity for QBI. In this paper we demonstrate a major drawback of the GFA occuring in crossing fiber regions: the fiber integrity is heavily underestimated here. We present a new, directional anisotropy measure and compare it to the GFA using custom-designed fiber phantoms and Monte Carlo simulations. Furthermore, we present in-vivo data of the measure. With the expense of reduced CNR, the new measure allows a better quantification of fiber bundles in crossing regions and potentially yields additional information regarding non-dominant tracts within a voxel. |
Year | DOI | Venue |
|---|---|---|
2010 | 10.1117/12.839608 | Proceedings of SPIE |
Keywords | Field | DocType |
fractional anisotropy,microstructures,diffusion,diffusion tensor imaging,monte carlo simulation,anisotropy | Voxel,Diffusion MRI,Monte Carlo method,Anisotropy,Fiber,Fractional anisotropy,Optics,Contrast-to-noise ratio,Physics,Fiber bundle | Conference |
Volume | ISSN | Citations |
7623 | 0277-786X | 0 |
PageRank | References | Authors |
0.34 | 0 | 4 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Klaus H. Fritzsche | 1 | 23 | 5.59 |
| Frederik B. Laun | 2 | 59 | 4.90 |
| Bram Stieltjes | 3 | 193 | 55.84 |
| Hans-Peter Meinzer | 4 | 4 | 1.51 |