Title
Prediction of novel drugs for hepatocellular carcinoma based on multi-source random walk.
Abstract
Computational approaches for predicting drug-disease associations by integrating gene expression and biological network provide great insights to the complex relationships among drugs, targets, disease genes, and diseases at a system level. Hepatocellular carcinoma (HCC) is one of the most common malignant tumors with a high rate of morbidity and mortality. We provide an integrative framework to p...
Year
DOI
Venue
2017
10.1109/TCBB.2016.2550453
IEEE/ACM Transactions on Computational Biology and Bioinformatics
Keywords
Field
DocType
Drugs,Diseases,Gene expression,Proteins,Electronic mail,Databases,Chemicals
Drug repositioning,Disease,Toxicogenomics,Hepatocellular carcinoma,Computer science,Biological network,Interaction network,Regorafenib,KEGG,Bioinformatics
Journal
Volume
Issue
ISSN
14
4
1545-5963
Citations 
PageRank 
References 
1
0.34
0
Authors
7
Name
Order
Citations
PageRank
Yu Liang12112.01
Ruidan Su211.02
Bingbo Wang353.87
Long Zhang410.34
Yapeng Zou510.34
Jing Zhang612.03
Lin Gao713729.86