Title
Multivariate combination of magnetization transfer, T2* and B0 orientation to study the myelo-architecture of the in vivo human cortex.
Abstract
Recently, T2* imaging at 7Tesla (T) MRI was shown to reveal microstructural features of the cortical myeloarchitecture thanks to an increase in contrast-to-noise ratio. However, several confounds hamper the specificity of T2* measures (iron content, blood vessels, tissues orientation). Another metric, magnetization transfer ratio (MTR), is known to also be sensitive to myelin content and thus would be an excellent complementary measure because its underlying contrast mechanisms are different than that from T2*. The goal of this study was thus to combine MTR and T2* using multivariate statistics in order to gain insights into cortical myelin content.
Year
DOI
Venue
2015
10.1016/j.neuroimage.2015.06.033
NeuroImage
Keywords
Field
DocType
MTR,T2*,B0 orientation,Myeloarchitecture,ICA,Brodmann
Diffusion MRI,Communication,Multivariate statistics,Psychology,Cognitive psychology,Correlation,Magnetization transfer,Independent component analysis,Cerebral cortex,Nuclear magnetic resonance,Magnetic resonance imaging,Myelin
Journal
Volume
ISSN
Citations 
119
1053-8119
16
PageRank 
References 
Authors
0.64
24
4
Name
Order
Citations
PageRank
G. Mangeat1160.64
sindhuja t govindarajan2160.97
Caterina Mainero3816.17
Julien Cohen-Adad447229.21