Title | ||
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Transcranial cortex stimulation and fMRI: Electrophysiological correlates of dual-pulse BOLD signal modulation |
Abstract | ||
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Are the local hemodynamic changes in BOLD-fMRI correlated to increased or decreased neuronal activity or both? We combined transcranial electrical cortex stimulation (TES) with simultaneous fMRI and electromyographic (EMG) recording to study the influence of inhibitory and excitatory neuronal activity on the concomitant BOLD signal change. Unilateral or bilateral TES was applied with a postero-anterior orientation. This activates pyramidal cells transsynaptically and allows for the induction of cortical inhibition and excitation of the pyramidal cell, respectively. In this project interhemispheric inhibition (IHI) served as an in vivo model to investigate electrophysiologically well defined inhibitory and excitatory effects. |
Year | DOI | Venue |
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2008 | 10.1016/j.neuroimage.2007.11.057 | NeuroImage |
Keywords | Field | DocType |
Interhemispheric inhibition,Excitation,Cortex stimulation,Human motor cortex,fMRI,BOLD,Neurovascular coupling | Cortex (botany),Pyramidal cell,Neuroscience,Premovement neuronal activity,Psychology,Inhibitory postsynaptic potential,Excitatory postsynaptic potential,Stimulus (physiology),Primary motor cortex,Electrophysiology | Journal |
Volume | Issue | ISSN |
40 | 2 | 1053-8119 |
Citations | PageRank | References |
0 | 0.34 | 5 |
Authors | ||
5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Jan Brocke | 1 | 0 | 0.34 |
S Schmidt | 2 | 4 | 1.18 |
Kerstin Irlbacher | 3 | 0 | 0.34 |
Radoslaw Martin Cichy | 4 | 70 | 8.79 |
Stephan A Brandt | 5 | 38 | 5.39 |