Title | ||
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New in silico approach to assessing RNA secondary structures with non-canonical base pairs |
Abstract | ||
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The function of RNA is strongly dependent on its structure, so an appropriate recognition of this structure, on every level of organization, is of great importance. One particular concern is the assessment of base-base interactions, described as the secondary structure, the knowledge of which greatly facilitates an interpretation of RNA function and allows for structure analysis on the tertiary level. The RNA secondary structure can be predicted from a sequence using in silico methods often adjusted with experimental data, or assessed from 3D structure atom coordinates. Computational approaches typically consider only canonical, Watson-Crick and wobble base pairs. Handling of non-canonical interactions, important for a full description of RNA structure, is still very difficult. |
Year | DOI | Venue |
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2015 | 10.1186/s12859-015-0718-6 | BMC Bioinformatics |
Keywords | Field | DocType |
RNA, Secondary structure, Non-canonical base pairs, RNApdbee, RNAComposer | RNA,Nucleic acid structure,Biology,Bioinformatics,Wobble base pair,Protein secondary structure,Base pair,Nucleic acid secondary structure,DNA microarray,In silico | Journal |
Volume | Issue | ISSN |
16 | 1 | 1471-2105 |
Citations | PageRank | References |
6 | 0.54 | 10 |
Authors | ||
8 |
Name | Order | Citations | PageRank |
---|---|---|---|
Agnieszka Rybarczyk | 1 | 13 | 3.77 |
Natalia Szostak | 2 | 11 | 1.58 |
Maciej Antczak | 3 | 30 | 6.41 |
Tomasz Zok | 4 | 26 | 2.89 |
Mariusz Popenda | 5 | 73 | 6.64 |
R W Adamiak | 6 | 75 | 6.71 |
Jacek Blazewicz | 7 | 1064 | 154.23 |
Marta Szachniuk | 8 | 97 | 12.33 |