Title
New in silico approach to assessing RNA secondary structures with non-canonical base pairs
Abstract
The function of RNA is strongly dependent on its structure, so an appropriate recognition of this structure, on every level of organization, is of great importance. One particular concern is the assessment of base-base interactions, described as the secondary structure, the knowledge of which greatly facilitates an interpretation of RNA function and allows for structure analysis on the tertiary level. The RNA secondary structure can be predicted from a sequence using in silico methods often adjusted with experimental data, or assessed from 3D structure atom coordinates. Computational approaches typically consider only canonical, Watson-Crick and wobble base pairs. Handling of non-canonical interactions, important for a full description of RNA structure, is still very difficult.
Year
DOI
Venue
2015
10.1186/s12859-015-0718-6
BMC Bioinformatics
Keywords
Field
DocType
RNA, Secondary structure, Non-canonical base pairs, RNApdbee, RNAComposer
RNA,Nucleic acid structure,Biology,Bioinformatics,Wobble base pair,Protein secondary structure,Base pair,Nucleic acid secondary structure,DNA microarray,In silico
Journal
Volume
Issue
ISSN
16
1
1471-2105
Citations 
PageRank 
References 
6
0.54
10
Authors
8
Name
Order
Citations
PageRank
Agnieszka Rybarczyk1133.77
Natalia Szostak2111.58
Maciej Antczak3306.41
Tomasz Zok4262.89
Mariusz Popenda5736.64
R W Adamiak6756.71
Jacek Blazewicz71064154.23
Marta Szachniuk89712.33