Title | ||
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A computational method for designing diverse linear epitopes including citrullinated peptides with desired binding affinities to intravenous immunoglobulin. |
Abstract | ||
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BackgroundUnderstanding the interactions between antibodies and the linear epitopes that they recognize is an important task in the study of immunological diseases. We present a novel computational method for the design of linear epitopes of specified binding affinity to Intravenous Immunoglobulin (IVIg). |
Year | DOI | Venue |
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2016 | 10.1186/s12859-016-1008-7 | BMC Bioinformatics |
Keywords | Field | DocType |
Protein binding, Machine learning, Antibodies, Protein design | Epitope,Plasma protein binding,Biology,Ligand (biochemistry),Immunological diseases,Protein design,Bioinformatics,Affinities,DNA microarray,Antibody | Journal |
Volume | Issue | ISSN |
17 | 1 | 1471-2105 |
Citations | PageRank | References |
0 | 0.34 | 18 |
Authors | ||
14 |
Name | Order | Citations | PageRank |
---|---|---|---|
Rob Patro | 1 | 111 | 12.98 |
Raquel Norel | 2 | 0 | 1.01 |
Robert J Prill | 3 | 12 | 1.35 |
Julio Saez-Rodriguez | 4 | 911 | 67.01 |
Peter Lorenz | 5 | 0 | 0.34 |
Felix Steinbeck | 6 | 0 | 0.34 |
Bjoern Ziems | 7 | 0 | 0.34 |
Mitja Luštrek | 8 | 410 | 54.52 |
Nicola Barbarini | 9 | 69 | 5.71 |
Alessandra Tiengo | 10 | 18 | 1.11 |
Riccardo Bellazzi | 11 | 1313 | 141.89 |
Hans-Jürgen Thiesen | 12 | 27 | 2.86 |
Gustavo Stolovitzky | 13 | 738 | 51.84 |
Carl Kingsford | 14 | 695 | 54.27 |