Title | ||
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MEGAHIT: an ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph. |
Abstract | ||
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MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time-and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252Gbps in 44.1 and 99.6h on a single computing node with and without a graphics processing unit, respectively. MEGAHIT assembles the data as a whole, i.e. no pre-processing like partitioning and normalization was needed. When compared with previous methods on assembling the soil data, MEGAHIT generated a three-time larger assembly, with longer contig N50 and average contig length; furthermore, 55.8% of the reads were aligned to the assembly, giving a fourfold improvement. |
Year | DOI | Venue |
---|---|---|
2015 | 10.1093/bioinformatics/btv033 | BIOINFORMATICS |
Field | DocType | Volume |
CUDA,Source code,Computer science,Parallel computing,Metagenomics,Contig,De Bruijn graph,Bioinformatics | Journal | 31 |
Issue | ISSN | Citations |
10 | 1367-4803 | 46 |
PageRank | References | Authors |
1.92 | 6 | 5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Dinghua Li | 1 | 51 | 3.73 |
Chi-Man Liu | 2 | 46 | 1.92 |
Ruibang Luo | 3 | 60 | 2.69 |
Kunihiko Sadakane | 4 | 46 | 1.92 |
Tak-Wah Lam | 5 | 1860 | 164.96 |