Title
MEGAHIT: an ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph.
Abstract
MEGAHIT is a NGS de novo assembler for assembling large and complex metagenomics data in a time-and cost-efficient manner. It finished assembling a soil metagenomics dataset with 252Gbps in 44.1 and 99.6h on a single computing node with and without a graphics processing unit, respectively. MEGAHIT assembles the data as a whole, i.e. no pre-processing like partitioning and normalization was needed. When compared with previous methods on assembling the soil data, MEGAHIT generated a three-time larger assembly, with longer contig N50 and average contig length; furthermore, 55.8% of the reads were aligned to the assembly, giving a fourfold improvement.
Year
DOI
Venue
2015
10.1093/bioinformatics/btv033
BIOINFORMATICS
Field
DocType
Volume
CUDA,Source code,Computer science,Parallel computing,Metagenomics,Contig,De Bruijn graph,Bioinformatics
Journal
31
Issue
ISSN
Citations 
10
1367-4803
46
PageRank 
References 
Authors
1.92
6
5
Name
Order
Citations
PageRank
Dinghua Li1513.73
Chi-Man Liu2461.92
Ruibang Luo3602.69
Kunihiko Sadakane4461.92
Tak-Wah Lam51860164.96