Title
Parallel A-Star Multiple Sequence Alignment with Locality-Sensitive Hash Functions
Abstract
In this paper, we propose and evaluate a parallel solution for the exact Multiple Sequence Alignment problem based on the A-Star algorithm. In our parallel solution, we use a multi-index data structure, templates and a locality-sensitive hash function. The results were collected in two machines (4 cores and 32 cores), with real and synthetic sequence sets ranging from 3 to 14 sequences. We show that our parallel solution executes 2.89× and 4.77× faster than a state-of-the-art parallel MSA tool, with a proportional increase in memory usage, when comparing 2 hard instances of the benchmark Bali base reference set 1.
Year
DOI
Venue
2015
10.1109/CISIS.2015.50
2015 Ninth International Conference on Complex, Intelligent, and Software Intensive Systems
Keywords
Field
DocType
Multiple Sequence Alignment,Multicore parallel programming,A-Star
Data structure,Locality,Computer science,Instruction set,Parallel computing,Ranging,Memory management,Hash function,Multiple sequence alignment,A* search algorithm,Distributed computing
Conference
Citations 
PageRank 
References 
0
0.34
11
Authors
3
Name
Order
Citations
PageRank
Daniel Sundfeld151.87
George Teodoro215022.18
Alba Cristina Magalhaes Alves De Melo325333.90