Title
Seizure Prediction by Graph Mining, Transfer Learning, and Transformation Learning
Abstract
We present in this study a novel approach to predicting EEG epileptic seizures: we accurately model and predict non-ictal cortical activity and use prediction errors as parameters that significantly distinguish ictal from non-ictal activity. We suppress seizure-related activity by modeling EEG signal acquisition as a cocktail party problem and obtaining seizure-related activity using Independent Component Analysis. Following recent studies intricately linking seizure to increased, widespread synchrony, we construct dynamic EEG synchronization graphs in which the electrodes are represented as nodes and the pair-wise correspondences between them are represented by edges. We extract 38 intuitive features from the synchronization graph as well as the original signal. From this, we use a rigorous method of feature selection to determine minimally redundant features that can describe the non-ictal EEG signal maximally. We learn a one-step forecast operator restricted to just these features, using autoregression AR1. We improve this in a novel way by cross-learning common knowledge across patients and recordings using Transfer Learning, and devise a novel transformation to increase the efficiency of transfer learning. We declare imminent seizure based on detecting outliers in our prediction errors using a simple and intuitive method. Our median seizure detection time is 11.04﾿min prior to the labeled start of the seizure compared to a benchmark of 1.25﾿min prior, based on previous work on the topic. To the authors' best knowledge this is the first attempt to model seizure prediction in this manner, employing efficient seizure suppression, the use of synchronization graphs and transfer learning, among other novel applications.
Year
DOI
Venue
2015
10.1007/978-3-319-21024-7_3
Machine Learning and Data Mining in Pattern Recognition
Field
DocType
Volume
Autoregressive model,Synchronization,Feature selection,Pattern recognition,Computer science,Transfer of learning,Independent component analysis,Artificial intelligence,Blind signal separation,Machine learning,Ictal,Electroencephalography
Conference
9166
ISSN
Citations 
PageRank 
0302-9743
1
0.41
References 
Authors
24
4
Name
Order
Citations
PageRank
Nimit Dhulekar1143.08
Srinivas Nambirajan2161.54
Basak Oztan36410.31
Bülent Yener4107594.51