Title
Examining palpebral conjunctiva for anemia assessment with image processing methods.
Abstract
Examining the hemoglobin level of blood is an important way to achieve the diagnosis of anemia, but it requires blood drawing and blood test. Examining the color distribution of palpebral conjunctiva is a standard procedure of anemia diagnosis, which requires no blood test. However, since color perception is not always consistent among different people, we attempt to imitate the way of physical examination of palpebral conjunctiva to detect anemia, so that computers can identify anemia patients automatically in a consolidated manner for a screening process. In this paper we propose two algorithms for anemia diagnosis. The first algorithm is intended to be simple and fast, while the second one to be more sophisticated and robust, providing an option for different applications. The first algorithm consists of a simple two-stage classifier. In the first stage, we use a thresholding decision technique based on a feature called high hue rate (HHR) (extracted from the HSI color space). In the second stage, a feature called pixel value in the middle (PVM) (extracted from the RGB color space) is proposed, followed by the use of a minimum distance classifier based on Mahalanobis distance. In the second algorithm, we consider 18 possible features, including a newly added entropy feature, some improved features from the first algorithm, and 13 features proposed in a previous work. We use correlation and simple statistics to select 3 relatively independent features (entropy, binarization of HHR, and PVM of G component) for classification using a support vector machine or an artificial neural network. Finally, we evaluate the classification performance of the proposed algorithms in terms of sensitivity, specificity, and Kappa value. The experimental results show relatively good performance and prove the feasibility of our attempt, which may encourage more follow-up study in the future.
Year
DOI
Venue
2016
10.1016/j.cmpb.2016.08.025
Computer Methods and Programs in Biomedicine
Keywords
Field
DocType
Anemia,Images of palpebral conjunctiva,Color and texture features,Support vector machine,Artificial neural network
Computer vision,Color space,Computer science,RGB color space,Support vector machine,Hue,Mahalanobis distance,Blood drawing,Artificial intelligence,Thresholding,Classifier (linguistics)
Journal
Volume
ISSN
Citations 
137
0169-2607
0
PageRank 
References 
Authors
0.34
2
3
Name
Order
Citations
PageRank
Yiming Chen1519.12
Shaou-gang Miaou215817.58
Hongyu Bian300.34