Title
Automated mutual exclusion rules discovery for structured observational codes in echocardiography reporting.
Abstract
Structured reporting in medicine has been argued to support and enhance machine-assisted processing and communication of pertinent information. Retrospective studies showed that structured echocardiography reports, constructed through point-and-click selection of finding codes (FCs), contain pair-wise contradictory FCs (e.g., "No tricuspid regurgitation" and "Severe regurgitation") downgrading report quality and reliability thereof. In a prospective study, contradictions were detected automatically using an extensive rule set that encodes mutual exclusion patterns between FCs. Rules creation is a labor and knowledge-intensive task that could benefit from automation. We propose a machine-learning approach to discover mutual exclusion rules in a corpus of 101,211 structured echocardiography reports through semantic and statistical analysis. Ground truth is derived from the extensive prospectively evaluated rule set. On the unseen test set, F-measure (0.439) and above-chance level AUC (0.885) show that our approach can potentially support the manual rules creation process. Our methods discovered previously unknown rules per expert review.
Year
Venue
Field
2015
AMIA
Data mining,Observational study,Structured reporting,Computer science,Automation,Ground truth,Artificial intelligence,Natural language processing,Mutual exclusion,Statistical analysis,Test set
DocType
Volume
Citations 
Conference
2015
0
PageRank 
References 
Authors
0.34
0
7
Name
Order
Citations
PageRank
Thomas A. Forsberg100.34
Merlijn Sevenster29813.33
Szymon Bieganski311.06
Puran Bhagat400.34
Melvin Kanasseril500.34
Yugang Jia6385.04
Kirk Spencer701.01